Chronic glomerulonephritis was diagnosed in a 34-year-old patient 3 years ago. Edema has developed within the last 6 monthes. What caused the edema?
A. Hyperproduction of vasopressin
B. Hyperaldosteronism
C. Proteinuria
D. Liver disfunction of protein formation
E. Hyperosmolarity of plasma
After breathing with poisonous steams there is an increased quantity of slime in respiratory passages of a chemical production worker. What of respiratory tract epithelial cells participate in mucousa moistening?
A. Goblet cells
B. Endocrine cells
C. Fibroblasts
D. Intercalated cells
E. Langergans cells
Synthesis of phospholipids is disordered under the liver fat infiltration. Indicate which of the following substances can enhance the process of methylation during phospholipids synthesis?
A. Glucose
B. Citrate
C. Methionine
D. Glycerin
E. Ascorbic acid
The preventive radioprotector was given to a worker of a nuclear power station. What mechanism from the below mentioned is considered to be the main mechanism of radioprotection?
A. Increasing of respiration
B. Inhibition of free radicals formation
C. Activation of oxidation reactions
D. Prevention of tissue’s hypoxia
E. Increasing of tissue blood supply
104 Scraps of the mycelium of a fungus, spores, air bubbles and fat drops were discovered on microscopy of the patient's hair excluded from the infected areas. What fungus disease is characterised by this microscopic picture?
A. Trichophytosis
B. Microspory
C. Sporotrichosis
D. Epidermophytosis
E. Favus
105 A mother of a newborn complains of her baby's constant belching with undigested milk. Which developmental anomaly is it an evidence of?
A. Esophageal atresia
B. Anal atresia
C. Labium leporium
D. Faux lupinum
E. Esophageal fistula
A 45-year-old man fell on the right knee and felt the acute pain in the joint. On examination: severe edema on the anterior surface of the knee joint. Crunching sounds are heard while moving the joint. Which bone is destroyed?
A. Head of the thigh bone
B. Right epicondyle of the thigh
C. Neck of the thigh bone
D. Left epicondyle of the thigh
E. Knee-cap
During complicated labour the symphysis pubis ruptured. What organ can be damaged mostly?
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A. Urinary blader
B. Ovaria
C. Uterine tubes
D. Rectum
E. Uterus
The patient with pneumonia was treated with antibiotics for a long period. After treatment patient complains of frequent and watery stool, abdomenal pain. What is the reason of intestine function disorder?
A. Hereditary enzyme defect
B. Antibiotics toxic influence on the GIT
C. Intestinal disbacteriosis development
D. Autoimmune reaction development
E. Bacteria toxins influence
The formation of a secondary mediator is obligatory in membrane-intracellular mechanism of hormone action. Point out the substance that is unable to be a secondary mediator:
A. Diacylglycerol
B. CAMP
C. Inositol-3,4,5-triphosphate
D. $Ca^{2+}$
E. Glycerol
Punctata hemorrhage was found out in the patient after application of a tourniquet. With disfunction of what blood cells is it connected?
A. Monocytes
B. Eosinophiles
C. Neutrophiles
D. Lymphocytes
E. Platelets
Analeptical remedy of reflective type from the H-cholinomimetics group was given to the patient for restoration of breathing after poisoning with carbon monoxide. What medicine was prescribed to the patient?
A. Mesaton
B. Pentamin
C. Atropine sulphate
D. Lobeline hydrochloride
E. Adrenalin hydrochloride
A healthy woman has three sons affected by color blindness who were born after her two marriages. Children both of her husbands are healthy. What is the most possible pattern of inheritance of this disease?
A. X-linked recessive
B. Autosomal recessive
C. Y-linked
D. Autosomal dominant
E. X-linked dominant
Methotrexate (structural analogue of the folic acid which is competitive inhibitor of the dihydrofolatreductase) is prescribed for treatment of the malignant tumour. On which level does methotrexate hinder synthesis of the nucleic acids?
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A. Reparation
B. Mononucleotide synthesis
C. Replication
D. Processing
E. Transcription
Pyruvate concentration in the patient’s urine has increased 10 times from normal amount. What vitamin deficiency can be the reason of this change:
A. Vitamin B6
B. Vitamin A
C. Vitamin E
D. Vitamin C
E. Vitamin B1
A patient suffering from trombophlebitis of deep veins suddenly died. The autopsy has shown freely lying red friable masses with dim crimped surface in the trunk and bifurcation of the pulmonary artery. What pathologic process was revealed by the morbid anatomist?
A. Thrombosis
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