A. Decreased activity of microsomal liver enzymes
B. Delayed urinary excretion of the preparation
C. Cumulation of the preparation
D. Genetic insufficiency of glucose 6-phosphate dehydrogenase
E. Drug potentiation by other preparations
An intraoperational biopsy of mammary gland has revealed the signs of atypical tissue presented by disorder of parenchyma stroma proportion with domination of the last, gland structures of different size and shape, lined with single-layered proliferative epithelium. What is the most probable diagnosis?
A. Mastitis
B. Fibroadenoma
C. Noninfiltrative cancer
D. Infiltrative cancer
E. Papilloma
Inhibition of б -motoneuron of the extensor muscles was noticed after stimulation of б -motoneuron of the flexor muscles during the experiment on the spinal cord. What type of inhibition is this process based upon?
A. Depolarizational
B. Recurrent
C. Lateral
D. Presynaptic
E. Reciprocal
Desulfiram is widely used in medical practice to prevent alcocholism. It inhibits aldehyde dehydrogenase. Increased level of what metabolite causes aversion to alcochol?
A. Methanol
B. Acetaldehyde
C. Malonyl aldehyde
D. Ethanol
E. Propionic aldehyde
A 60-year-old patient fell ill with obturative jaundice as a result of malignant tumour of the big papillary of the duodenum. Lumen of what anatomical structure is compressed by tumour?
A. Left hepatic duct
B. Right hepatic duct
C. Common hepatic duct
D. Hepatopancreatic ampulla
E. Cystic duct
A 38-year-old patient died during intractable attack of bronchial asthma. Histologic examination revealed mucus accumulation in bronchial lumen, a lot of fat cells (labrocytes) in the wall of bronches, many of them are in the state of degranulation, there are also a lot of eosinophils. What pathogenesis of bronchial changes is it?
A. Atrophy
B. Cytotoxic, cytolytic action of antibodies
C. Granulomatosis
D. Immunocomplex mechanism
E. Cellular cytolysis
36 Part of alveoles of a preterm infant didn't spread because of enhanced elastic recoil of lungs. How can this recoil be reduced?
A. By artificial pulmonary ventilation
B. By glycose introduction
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C. By pure oxygene inhalation
D. By surfactant introduction
E. By fluid suction from the respiratory tracts
37 Autopsy of a man who died from chronic cardiaovascular collapse revealed "tiger heart". Sidewards of endocardium a yellowish-white banding can be seen; myocardium is dull, dark-yellow. What process caused this pathology?
A. Fatty parenchymatous degeneration
B. Carbohydrate degeneration
C. Fatty vascular-stromal degeneration
D. Amyloidosis
E. Hyaline degeneration
38 A patient's blood was analyzed and the decreased erythrocyte's sedimentation rate (ESR) was discovered. What disease from the listed below is accompanied with decreased ESR?
A. Hepatitis
B. Polycytemia
C. Vitamin B deficiency
D. Splenomegaly
E. Myocardial infarction
Tuberculine was introduced intracutaneously to the child for tuberculin test. Marked hyperemia, tissue infiltration developed on the place of injection in 24 hours. What mechanism caused these modifications?
A. Antibody cytotoxity
B. Reagin type cytotoxity
C. Granuloma formation
D. Immunocomplex cytotoxity
E. Cell cytotoxity
A 34-year-old patient was diagnosed with chronic glomerulonephritis 3 years ago. Edema have developed within the last 6 months. What caused the edema?
A. Hyperosmolarity of plasma
B. Hyperproduction of vasopressin
C. Proteinuria
D. Hyperaldosteronism
E. Liver dysfunction of protein formation
A 57-year-old patient was admitted to the gastroenterological department with suspicion of Zollinger-Ellison syndrom because of rapid increase of gastrin level in the blood serum. What is the most probable disorder of the secretory function of stomach?
A. Hypoacidic hypersecretion
B. Hyperacidic hypersecretion
C. Hypoacidic hyposecretion
D. Achylia
E. Hyperacidic hyposecretion
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A 54-year-old man was admitted to the hospital with complaints of pain in the right subcostal region, vomiting with blood. Objectively: enlarged liver, varicose veins in the stomach and esophagus. Disfunction of what vessel is likely to have taken place?
A. Aorta abdominalis
B. Vena hepatica
C. Vena cava inferior
D. Vena porta
E. Vena cava superior
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