Chromosomes were revealed on karyotype examination of the 5-year-old girl. One of the



Th pair of chromosomes is longer than usual due to connected chromosome from the 21 pair.

What type of mutation does this girl have?

A Translocation

B Deletion

C Inversion

D Insufficiency

E Duplication

      44

A pregnant woman had been having toxicosis with severe repeated vomiting for 24 hours. In the

End of the day there appeared tetanic convulsions and fluid loss. What shift of acid-base state

Caused these changes?

A Excretory alkalosis

B Gaseous alkalosis

C Gaseous acidosis

D Metabolic acidosis

E Excretory acidosis

      45

Genetic structure of eukaryote is "exon-intron-exon". This structure-functional organization of

Gene caused transcription peculiarities. What will be pro-i-RNA according to the schema?

A Exon-intron-exon

B Exon-exon-intron

C Exon-exon

D Intron-exon

E Exon-intron

      46

Medical examination at the military registration and enlistment office revealed that a 15-year-old

Boy was high, with eunuchoid body proportions, gynecomastia, female pattern of pubic hair

Distribution. The boy had also fat deposits on the thighs, no facial hair, high voice, subnormal

Intelligence quotient. Which karyotype corresponds with this disease?

A 47, XXY

B 45, XO

C 46, XX

D 46, XY

E 47, XXX

      47

RNA that contains AIDS virus penetrated into a leukocyte and by means of reverse

Transcriptase forced a cell to synthetize a viral DNA. This process is based upon:

A Reverse transcription

B Operon repression

C Reverse translation

D Operon depression

E Convariant replication

      48

According to the model of double DNA helix that was suggested by Watson and Creek, it was

Established that one of chains would not be lost during replication and the second chain would

Be synthesized complementary to the first one. What way of replication is it?

A Semiconservative

B Analogous

C Identical

D Dispersed

E Conservative

      49

A teenager was irradiated with high radiation dose that resulted in serious damages of lymphoid

System, lysis of many lymphocytes. Restoration of normal hemogram is possible due to the

Functioning of the following gland:

A Thymus

B Thyroid

C Liver

D Pancreas

E Adrenal

      50

It was revealed that T-lymphocytes were affected by HIV. Virus enzyme - reverse transcriptase

RNA-dependent DNA polymerase) - catalyzes the synthesis of:

A DNA on the matrix of virus mRNA

B Virus informational RNA on the matrix of DNA

C DNA on virus ribosomal RNA

D Viral DNA on DNA matrix

E mRNA on the matrix of virus protein

      51

A patient after pathological process has a thickened alveolar membrane. The direct

consequence of the process will be the reduction of:

A Diffuse lung capacity

B Oxygen capacity of blood

C Minute respiratory capacity

D Alveolar lung ventilation

E Reserve expiratiory capacity

      52

Autopsy of a newborn boy revealed polydactylia, microcephalia, cheiloschisis and uranoschisis

As well as hypertrophy of parenchimatous organs. These defects correspond with the

Description of Patau's syndrome. What is the most probable cause of this pathology?

A Trisomy of the 13th chromosome

B Trisomy of the 18th chromosome

C Trisomy of the 21st chromosome

D Nondisjunction of sex chromosomes

E Partial monosomy

      53

An ovary specimen stained by hematoxylin-eosin presents a follicle, where cells of follicular

Epithelium are placed in 1-2 layers and have cubic form, there is a bright-red membrane around

The ovocyte. What follicle is it?

A Primary

B Primordial

C Secondary

D Mature

E Atretic

      54

A patient has symptoms of inflammation of urogenital tracts. Examination of a vaginal smear

Revealed big monocellular, pear-shaped organisms with the pointed spike at the posterior end of

Body, big nucleus and undulating membrane. What protozoa were found in the smear?

A Trichomonas vaginalis

B Trichomonas hominis

C Trichomonas buccalis

D Trypanosoma gambiense

E Lamblia intestinalis

      55

During regular examination of schoolchildren it was revealed that a 10 year old girl had

Asymmetric oval eggs with a larva in the scrape from her perianal folds. What diagnosis should

Be made?

A Enterobiasis

B Ascariasis

C Amebiasis

D Trichocephalosis

E Ankylostomiasis

      56


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