Examination of a patient revealed II grade obesity. It is known that he consumes a lot of sweets
And rich food, has sedentary way of life. That's why anabolic metabolism has the priority in his
Organism. Which of the following pathways is amphibolic?
A Cycle of tricarboxylic acids
B Glyconeogenesis
C Lipolysis
D Glycolysis
E Fatty acids oxidation
165
Surgical removal of a part of stomach resulted in disturbed absorption of vitamin B12, it is
Excreted with feces. The patient was diagnosed with anemia. What factor is necessary for
Absorption of this vitamin?
A Gastromucoprotein
B Gastrin
C Hydrochloric acid
D Pepsin
E Folic acid
166
A newborn develops dyspepsia after the milk feeding. When the milk is substituted by the
Glucose solution the dyspepsia symptoms disappear. The newborn has the subnormal activity of
The following enzyme:
A Lactase
B Invertase
C Maltase
D Amylase
E Isomaltase
167
Patients who suffer from severe diabetes and don't receive insulin have metabolic acidosis.
This is caused by increased concentration of the following metabolites:
A Ketone bodies
B Fatty acids
C Unsaturated fatty acids
D Triacylglycerols
E Cholesterol
168
A 4 year old child with hereditary renal lesion has signs of rickets, vitamin D concentration in
Blood is normal. What is the most probable cause of rickets development?
A Impaired synthesis of calcitriol
B Increased excretion of calcium
C Hyperfunction of parathyroid glands
D Hypofunction of parathyroid glands
E Lack of calcium in food
169
A patient presents with dysfunction of cerebral cortex accompanied by epileptic seizures. He
Has been administered a biogenic amine synthetized from glutamate and responsible for central
Inhibition. What substance is it?
A Gamma-amino butyric acid
B Serotonin
C Dopamine
D Acetylcholine
E Histamine
170
Toxic affection of liver results in dysfunction of protein synthesis. It is usually accompanied by
The following kind of dysproteinemia:
A Absolute hypoproteinemia
B Relative hypoproteinemia
C Absolute hyperproteinemia
D Relative hyperproteinemia
E Paraproteinemia
171
A 6 year old child was delivered to a hospital. Examination revealed that the child couldn't fix his
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Eyes, didn't keep his eyes on toys, eye ground had the cherry-red spot sign. Laboratory
Analyses showed that brain, liver and spleen had high rate of ganglioside glycometide. What
Congenital disease is the child ill with?
A Tay-Sachs disease
B Wilson's syndrome
C Turner's syndrome
D Niemann-Pick disease
E MacArdle disease
172
In clinical practice tuberculosis is treated with izoniazid preparation - that is an antivitamin able
To penetrate into the tuberculosis bacillus. Tuberculostatic effect is induced by the interference
With replication processes and oxidation-reduction reactions due to the buildup of
Pseudo-coenzyme:
A NAD
B FAD
C FMN
D TDP
E CoQ
173
A newborn child was found to have reduced intensity of sucking, frequent vomiting, hypotonia.
Urine and blood exhibit increased concentration of citrulline. What metabolic process is
Disturbed?
A Ornithinic cycle
B Tricarboxylic acid cycle
C Glycolysis
D Glyconeogenesis
E Cori cycle
174
A male patient has been diagnosed with acute radiation disease. Laboratory examination
Revealed a considerable reduction of platelet serotonin level. The likely cause of platelet
Serotonin reduction is the disturbed metabolism of the following substance:
A 5-oxytryptofane
B Tyrosine
C Histidine
D Phenylalanine
E Serine
175
Dietary intake of a 30 year old nursing woman contains 1000 mg of calcium, 1300 mg of
Phosphorus and 20 mg of iron per day. It is necessary to change content of these mineral
Substances in the following way:
A To increase phosphorus content
B To increase calcium content
C To reduce fluorine content
D To increase iron content
E To reduce iron content
176
Cardinal symptoms of primary hyperparathyroidism are osteoporosis and renal lesion along with
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Development of urolithiasis. What substance makes up the basis of these calculi in this
Disease?
A Calcium phosphate
B Uric acid
C Cystine
D Bilirubin
E Cholesterol
177
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