Mucus with some eosinophils, there is sclerosis of alveolar septums, dilatation of alveole lumen.
What mechanism of development of hypersensibility reaction took place?
A Reagin reaction
B Cytotoxic reaction
C Immunocomplex reaction
D Cytolysis determined by lymphocytes
E Granulomatosis
138
Desulfiram is widely used in medical practice to prevent alcocholism. It inhibits aldehyde
Dehydrogenase. Increased level of what metabolite causes aversion to alcochol?
A Acetaldehyde
B Ethanol
C Malonyl aldehyde
D Propionic aldehyde
E Methanol
139
A 1-year-old child with symptoms of muscle involvement was admitted to the hospital.
Examination revealed carnitine deficiency in his muscles. What process disturbance is the
Biochemical basis of this pathology?
A Transporting of fatty acids to mitochodrions
B Regulation of Ca2+ level in mitochondrions
C Substrate phosphorylation
D Lactic acid utilization
E Actin and myosin synthesis
140
The patient with complaints of permanent thirst applied to the doctor. Hyperglycemia, polyuria
And increased concentration of 17-ketosteroids in the urine were revealed. What disease is the
Most likely?
A Steroid diabetes
B Insulin-dependent diabetes mellitus
C Myxoedema
D Type I glycogenosis
E Addison's disease
141
Index of pH of the blood changed and became 7,3 in the patient with diabetus mellitus. Detecting
Of the components of what buffer system is used while diagnosing disorder of the acid-base
Equilibrium?
A Bicarbonate
B Phosphate
C Hemoglobin
D Oxyhemoglobin
E Protein
142
A man got poisoned with mushrooms. They contain muscarine that stimulates muscarinic
Cholinoreceptors. What symptom is typical for poisoning with inedible mushrooms?
A Miosis
B Mydriasis
C Bronchi dilation
D Heart rate rise
E Arterial pressure rise
143
As a result of posttranslative modifications some proteins taking part in blood coagulation,
Particularly prothrombin, become capable of calcium binding. The following vitamin takes part in
This process:
A K
B C
C A
D B1
E B2
144
Objective examination of a patient revealed: slender figure, big skull, highly developed frontal
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Region of face, short extremities. What constitutional type is it characteristic for?
A Respiratory
B Muscular
C Digestive
D Cerebral
E Mixed
145
A 38-year-old patient died during intractable attack of bronchial asthma. Histologic examination
Revealed mucus accumulation in bronchial lumen, a lot of fat cells (labrocytes) in the wall of
Bronches, many of them are in the state of degranulation, there are also a lot of eosinophils.
What pathogenesis of bronchial changes is it?
A Atopy
B Cytotoxic, cytolytic action of antibodies
C Immunocomplex mechanism
D Cellular cytolysis
E Granulomatosis
146
Diabetes mellitus causes ketosis as a result of activated oxidation of fatty acids. What
Disorders of acid-base equilibrium may be caused by excessive accumulation of ketone bodies
In blood?
A Metabolic acidosis
B Metabolic alcalosis
C Any changes woun't happen
D Respiratory acidosis
E Respiratory alcalosis
147
A woman with 0 (I) bllod group has born a child with AB blood group. This woman's husband has
A blood group. What genetic interaction explains this phenomenon?
A Recessive epistasis
B Codominance
C Polymery
D Incomplete dominance
E Complementation
148
Osteolaterism is charcterized by a decrease in collagen strength caused by much less intensive
Formation of cross-links in collagen fibrils. This phenomenon is caused by the low activity of the
Following enzyme:
A Lysyl oxidase
B Monoamino-oxidase
C Prolyl hydroxylase
D Lysyl hydroxylase
E Collagenase
149
Depressions and emotional insanities result from the deficit of noradrenalin, serotonin and other
Biogenic amines in the brain. Their concentration in the synapses can be increased by means
Of the antidepressants that inhibit the following enzyme:
A Monoamine oxidase
B Diamine oxidase
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C L-amino-acid oxidase
D D-amino-acid oxidase
E Phenylalanine-4-monooxygenase
150
A 3 year old child with symptoms of stomatitis, gingivitis and dermatitis of open skin areas was
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