A child has got galactosemia. Concentration of glucose in blood has not considerably changed. Deficiency of what enzyme caused this illness?

A. Galactokinase

B. Phosphoglucomutase

C. Amylo-1,6-glucosidase

D. Galactose-1-phosphate uridyltransferase

E. Hexokinase

A 60-year-old man felt asleep after cerebral hemorrhage for a long time. Damage of what structure caused this state?

A. Black substance

B. Nuclears of the cerebral nerves

C. Hippocampus

D. Cortex of the large hemispheres

E. Reticular formation

A patient with thrombophlebitis of lower extremities had got chest pains, blood spitting, growing respiratory failure that caused his death. Autopsy revealed multiple pulmonary infarctions. What is the most probable reason of their development?

A. Pulmonary artery embolism

B. Pulmonary venous thrombosis

C. Bronchial artery thrombosis

D. Pulmonary artery thrombosis

E. Bronchial artery embolism

Diabetes mellitus causes ketosis as a result of activated oxidation of fatty acids. What disorders of acid-base equilibrium may be caused by excessive accumulation of ketone bodies in blood?

A. Respiratory acidosis

B. Metabolic alcalosis

C. Any changes woun't happen

D. Metabolic acidosis

E. Respiratory alcalosis

To anaesthetize the surgical treatment of burn surface, a patient was intravenously injected a medication for short-acting narcosis. 1 minute later the patient being under anaesthesia showed increased blood pressure, tachycardia, increased tone of skeletal muscles; reflexes remained. After recovering from anaesthesia the patient had disorientation and visual hallucinations. What medication was the patient injected?

A. Sombrevin

B. Diethyl ether

C. Nitrous oxide

D. Ketamine

E. Thiopental sodium

A 42-year-old man suffering from gout has increased level of urinary acid in blood. Allopurinol was prescribed to decrease the level of urinary acid. Competitive inhibitor of what enzyme is allopurinol?

A. Xanthine oxidase

B. Adenine phosphoribosiltransferase

C. Adenosine deaminase

D. Guanine deaminase

E. Hypoxanthine phosphoribosiltransferase

 122 During the fetal period of the development in the vascular system of the fetus a large arterial (Botallo's) duct is functioning which converts into lig.arteriosum after birth. What anatomical formations does this duct connect?

A. Aorta and superior vena cava

B. Pulmonary trunk and aorta

C. Aorta and inferior vena cava

D. Right and left auricles

E. Pulmonary trunk and superior vena cava

Cerebral trauma caused increase of ammonia formation. What aminoacid takes part in removal of ammonia from cerebral tissue?

A. Tryptophan

B. Glutamic

C. Lisine

D. Valine

E. Tyrosine

Upper neck node of sympathetic trunk was removed from the rabbit on experiment. Reddening and increased temperature of the skin of head is observed. What disorder of peripheral circulation of the blood has developed?

A. Venous hyperemia

B. Stasis

C. Neurotonic arterial hyperemia

D. Neuroparalytic arterial hyperemia

E. Metabolic arterial hyperemia

 125 An 18-year-old patient has enlarged inguinal lymphnodes, they are painless, thickened on palpation. In the area of genital mucous membrane there is a small-sized ulcer with thickened edges and "laquer" bottom of greyish colour. What is the most probable diagnosis?

A. Lepra

B. Trophic ulcer

C. Syphilis

D. Gonorrhea

E. Tuberculosis

It is planned to use the territory of an old cattle burial ground (which is not used for more than 50 years) for building houses. But ground analysis revealed presence of the pathogen of a very dangerous illness. Which of the indicated microorgonisms is likely to remain in the ground for such a long time?

A. Yersinia pestis

B. Brucella abortus

C. Francisella tularensis

D. Mycobacterium bovis

E. Bacillus anthracis

A 30-year-old woman was diagnosed with insufficiency of exocrinous function of pancreas. Hydrolisis of what nutrients will be disturbed?

A. Fats, carbohydrates

B. Proteins, carbohydrates

C. Proteins, fats, carbohydrates

D. Proteins, fats

E. Proteins

On autopsy of the 58-year-old man it was revealed: mitral valve is deformed, thickened, not totally closed. Microscopically: foci of collagen fibers are eosinophilic, have positive fibrin reaction. The most likely it is:

A. Fibrinoid swelling

B. Amyloidosis

C. Hyalinosis

D. Mucoid swelling

E. Fibrinoid inflammation

A 39-year-old woman has madescence in the region of mammilla, a small ulcer with inflammatory hyperemia and cutaneous edema. Histologic examination of tissue sampling from this area revealed in the malpighian layer of thickened epidermis atypical cells with light and optically empty cytoplasm, with no intracellular bridges. Such cells were also found in the orifice of big mammal gland ducts. What is the most probable diagnosis?

A. Paget's disease

B. Intraductal cancer

C. Epidermoid cancer

D. Melanocarcinoma

E. Basal cell carcinoma

A 37-year-old man was admitted to the surgical department with the symptoms of acute pancreatitis: vomiting, diarrhea, bradycardia, hypotention, weakness, dehydration of the organism. What medicine should be used first of all?

A. Etaperazine

B. Ephedrine

C. No-spa

D. Platyphylline

E. Contrycal

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