A. Formation of polypeptide chains



B. Detaching of N-ended peptide

C. Hydroxylation of proline

D. Glycosylation of hydroxylysine residues

E. Removal of C-ended peptide from procollagen

After a serious viral infection a 3-year-old child has repeated vomiting, loss of consciousness, convulsions. Examination revealed hyperammoniemia. What may have caused changes of biochemical blood indices of this child?

A. Disorder of biogenic amines neutralization

B. Activated processes of aminoacids decarboxylation

C. Increased purtefaction of proteins in intestines

D. Disorder of ammonia neutralization in ornithinic cycle

E. Inhibited activity of transamination enzymes

When a patient with traumatic impairment of the brain was examined, it was discovered that he had stopped to distinguish displacement of an object on the skin. What part of the brain was damaged?

A. Occipital zone of the cortex

B. Posterior central gurus

C. Parietal zone of the cortex

D. Frontal central gurus

E. Frontal zone

A 7-year-old girl has signs of anemia. Laboratory examination revealed pyruvate kinase deficiency in erythrocytes. What process disturbance plays the main role in anemia development?

A. Tissue respiration

B. Peroxide decomposition

C. Anaerobic glycolysis

D. Aminoacids desamination

E. Oxidative phosphorylation

A pregnant woman had been having toxicosis with severe repeated vomiting for 24 hours. In the end of the day there appeared tetanic convulsions and fluid loss. What shift of acid-base state caused these changes?

A. Gaseous acidosis

B. Metabolic acidosis

C. Excretory alkalosis

D. Gaseous alkalosis

E. Excretory acidosis

A 55-year-old patient with continuing ventricular arrhythmias was admitted to the hospital. The patient is taking timolol drops for glaucoma, daily insulin injections for diabetes mellitus, and an ACE inhibitor for hypertension. You have decided to use phenytoin instead of procainamide. What is the reason?

A. The hypertensive effects of procainamide would aggravate the hypertension

B. The anticholinergic effect of procainamide would aggravate glaucoma

C. The cholinergic effects of procainamide would aggravate the diabetes

D. The local anesthetic effect of procainamide would aggravate the hypertension

E. The local anesthetic effect of procainamide would potentiate diabetes

A businessman came to India from South America. On examination the physician found that the patient was suffering from sleeping-sickness. What was the way of invasion?

A. After contact with sick dogs

B. As a result of mosquito's bites

C. Through dirty hands

D. As a result of bug's bites

E. With contaminated fruits and vegetables

A young man has a painlessl formation without marked borders in the soft tissues of his thigh. On the tissue bioptate the formation looks like flesh of fish and consists of immature fibroblast-like cells with multiple mitosis growing through the muscles. What is the most likely diagnosis?

A. Fibrosarcoma

B. Fibroma

C. Myoma

D. Myosarcoma

E. Cancer

 181 A person has steady HR not exceeding 40 bpm. What is the pacemaker of this person's heart rhythm?

A. Atrioventricular node

B. His' bundle

C. Purkinje's fibers

D. Sinoatrial node

E. Branches of His' bundle

Live vaccine was injected into the human body. Increasing activity of what connective tissue cells can be expected?

A. Fibroblasts and labrocytes

B. Macrophages and fibroblasts

C. Pigmentocytes and pericytes

D. Plasmocytes and lymphocytes

E. Adipocytes and adventitious cells

RNA-polymerase B(II) is blocked due to amanitine poisoning (poison of death-cup). It disturbs:

A. Reverse transcription

B. Synthesis of m-RNA

C. Maturation of m-RNA

D. Synthesis of t-RNA

E. Primers synthesis

An isolated cell of human heart automatically generates excitation impulses with frequency 60 times pro minute. What structure does this cell belong to?

A. Ventricle

B. Atrioventricular node

C. His' bundle

D. Sinoatrial node

E. Atrium

Autopsy revealed that right lung is enlarged, solid, there are fibrin layers on the pleura. Lung tissue is light grey color on incision with muddy liqued exudates. What lung disease are these symptoms typical for?

A. Fibrosing alveolitis

B. Croupous pneumonia

C. Interstitial pneumonia

D. Bronchopneumonia

E. Pulmonary gangrene

 186 Testosterone and it's analogs increase the mass of skeletal muscles that allows to use them for treatment of dystrophy. Due to interaction of the hormone with what cell substrate is this action caused?

A. Membrane receptors

B. Ribosomes

C. Nuclear receptors


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