Here is a matrix. Tick the table cells corresponding to things that most typically go together.

	Precau­tions	Dosage	Indica- ­tions	Side-effect	Shelf life	Storage condition	Mode of use
swallow
i.m. (i.v.)
in a cold place
pneumonia
rash
pregnancy
headache
vomiting
shake
orally
before (after, during) meals
3 times a day
reduces fever
bleeding
should be taken
consult a doctor
intolerance
out of reach of children
expiry date

3. What word/word combinations correspond to the ones in the right соlumn?

1. indication                      a. intramuscularly

2. side effect                     b. headache

3. allergic reaction             c. two years

4. shelf life                        d. keep away from heat

5. storage condition          e. nausea, vomiting

6. mode of use                  f. rash

7. dosage                           g. chew

8. administration               h. per kg of body weight

4. Use the new words in sentences of your own.

II. Reading.

1 . Match the English word combinations with their Ukrainian transla­tions.

1. skin diseases                               а) рецидив (повернення) хвороби

2. anti-inflammatory                       b) хвороби нирок

3. recurrence of the disease            c) протизапальний

4. diabetes mellitus                         d) хвороби шкіри

5. renal diseases                              e) цукровий діабет

2. Read the Septozyl package insert. Write out key words from each para­graph.

Composition neomycin sulfate____________

Indications___________________________

Application and dosage__________________

Side effects__________________________

Contraindications______________________

 

SEPTOZYL

Cream with Neomycin

Topical corticoid for use in skin diseases

Composition

Each one gram of cream contains:

5 mg Neomycin sulfate

1 mg 9a-fiuoro-16a-methylprednisolon

Septozyl cream is effective for topical use in skin diseases. The first active substance — a synthetic corticoid ester — has an anti-inflammatory and anti-aller­gic action, and the second component Neomycin sulfate has antibacterial activity. This composition is available in a specially formulated base, which is excellently tolerated by the skin. Septozyl cream is suitable for use in adults and children.

Indications

Eczema of varying type and localization, including infantile eczema. Vari­ous forms of dermatitis, sunburn, otitis externa, intertrigo and napkin rash. Vari­ous forms of neurodermatitis. Skin diseases especially psoriasis, lichen planus and chronic discoid lupus erythematosus. Itching of the pudenda and anus.

Application and dosage

Septozyl should be applied to the skin in a thin film several times daily. In some cases, one application a day will prove sufficient. After the skin has healed, Septozyl with neomycin should be applied one time daily for a further 1—2 weeks in order to prevent any recurrence of the disease.

Side effects

After a long-term use of Septozyl, and when the preparation is applied to ex­tensive areas of skin, there is a possibility of the following side effects appearing:

1) hyperglycaemia and glycosuria (in patients with a family history of diabe­tes mellitus);

2) increased potassium excretion, possibly resulting in hypokalaemic alkalo­sis;

3) hypertrichosis and acne;

4) sodium and water retention, giving rise to oedema and hypertension;

5) a negative nitrogen balance;

6) clinical picture of Cushing's syndrome;

7) delayed healing of surgical wounds;

8) prolonged treatment may cause adrenocoptical atrophy. Contraindications

- Pregnancy, particularly during the first three months.

- Severe renal diseases (excluding nephrosis).

- Psychoses, or a tendency to phychosis.

- Active tuberculosis.

- Infectious diseases.

- Tendency to haemorrage (in patients with peptic ulcer).

Drugs should be kept out of the reach of children. Tel. No. of centre for poi­soning cases: 7793777.

Packs: Cream in tubes of 15 g.

III. Post-reading activities

Answer the following questions.

1. What can you say about the composition of Septozyl?

2. What is Septozyl effective for?

3. What are the indications of Septozyl?

4. What do you know about the application of this medicine?

5. What are the side effects of Septozyl?

6. In what case is Septozyl contraindicated for women?

7. Is this drug recommended for those who have severe renal diseases?

8. Name some more contraindications of Septozyl.

Translate into English.

1. Для місцевого застосування.

2. Протиалергічна дія.

3. Різноманітні форми дерматитів.

4. Довготривале використання.

5. Вагітність.

6. Кровотеча.

IV. Speaking

Read the quotation and guess its meaning. Do you agree with it? Com­ment your point of view.

Half of the modern drugs could well be thrown out of the window, except that

the birds might eat them. (M.H. Fisher)

Notes: to throw — викидати; except — крім.

V. Supplement

1. Fill in the first part of the table.

Trade name	Indica-tions	Dosage	Precautions	Mode of use (Administration)
DIC (diclofenac)					What I know
Panadol
DIC (diclofenac)					What I have learned
Panadol

2. Fill in the second part of the table after reading the medication summaries.

 

 

3. Compare your ideas with your partner's.

Text 1

DIC

(Diclofenac)

Composition

a) Each enteric coated tablet contains Diclofenac Sodium 25 mg.

b) Each enteric coated tablet contains Diclofenac Sodium 50 mg.

c) Each enteric coated tablet contains Diclofenac Sodium 100 mg. DIC INJECTION

d)Each ml of injection contains Diclofenac Sodium 25 mg.

Description

DIC (Diclofenac) is a potent non-steroidal anti-inflammatory drug ( NSAID) with analgesic and antipyretic properties. It also has some uricosuric¹ effect. Di­clofenac inhibits cyclo-oxygenase activity with a reduction in the tissue production of prostaglandins such as PgF2 and PgE2. The anti-inflammatory effect, measured in the adjuvant induced arthritis model is greater than that of aspirin and similar to indomethacin.

Indications

■ Rheumatoid arthritis.

■ Osteoarthritis.

■ Low back pain and other acute musculoskeletal disorders such as tendoni­tis², tenosynovitis, bursitis, sprains³, strains and dislocations.

■ Ankylosing spondylitis⁴.

■ Acute gout.

■ Control of pain and inflammation in orthopaedic, dental and other minor surgery.

■  Juvenile chronic arthritis.

■  Postoperative pain.

■  Pain of renal colic.

Contraindications

Active or suspected peptic ulcer or gastrointestinal bleeding. Previous sensi­tivity to diclofenac sodium. Asthmatic patients in whom attacs of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAID's possessing prosta­glandin synthetase inhibiting activity.

Dosage and adminstration

A) Oral.

For symptomatic relief of rheumatoid arthritis, the usual daily dosage is 150 to 200 mg given in two to four divided doses.

For osteoarthritis, 100 to 150 mg is given daily in two or three divided doses.

For ankylosing spondylitis, 100 to 125 mg is given daily in four or five divided doses.

B) Parenteral.

75 mg i.m. 1—2 times daily by deep intragluteal injection for 2—3 days.

Precautions

DIC (Diclofenac) may be used cautiously in patients with history of dyspepsia⁵, or other g.i. disorders, blood coagulation disorders, severe hepatic or renal disease. Perform blood counts during long-term therapy. Safety in pregnancy, lactation and children has not been established.

Presentation

DIC tablets of 25 mg, 50 mg and 100 mg are available in pack of 10's and in bulk pack of 1000's.

DIC injection is available in clear glass ampoules of 3 ml.

Notes:

¹uricosuric — засіб, що допомагає виведенню сечової кислоти

²tendonitis — тендиніт (дистрофія тканини сухожилля)

³sprain — розтягнення зв'язок

⁴spondylitis — спондиліт (запалення всіх або деяких структурних елементів хребта)

⁵dyspepsia — диспепсія (розлад травлення)

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