Герпетическая генитальная инфекция. Цитомегаловирусная инфекция.



Алгоритм диагностики, тактика ведения беременных.

 

Герпес

The herpes simplex virus can infect women’s’:

Vagina, vulva, urethra, cervix, rectum

Vagina, cervix, rectum, vulva

Vulva, urethra, rectum

Vulva, cervix, urethra

Rectum, vulva, vagina

 

The disease is caused by the herpes simplex virus, often occurs:

Acutely

Subacute

Asymptomatic

In a chronic form

As a recurrent infection in vulva

 

The risk of neonatal herpes in the world today is:

Low

Insignificant

High

Very high

No risk

 

An important role in a viremia with herpes belongs (А.Ф. Пухнер, В.И. Козлова, 2010):

Red blood cells and white blood cells

Lymphocytes and leucocytes

Platelets and leucocytes

Monocytes and neutrophils

Eozinofilly

 

The role of red blood cells in chronic herpes infection is (А.Ф. Пухнер, В.И. Козлова, 2010):

They are a temporary carrier of the virus

In the red blood cells the virus replicates

They inactivate the virus

Provides constant of virus

The virus prolongs the life of red blood cells

 

The role of leucocytes in chronic herpes infection is:

They fix, but do not inactivate the herpes virus

They inactivate herpes virus

They lyse the herpes virus

They phagocytose virus and reproduce them

They rapidly are destroyed by virus

 

How the smear does look like in herpetic infection:

Are identified the mast cells

Are identified the "key cells"

Are identified the "naked" nucleus

Are identified the small cells with altered nuclei

Are revealed giant cells with intranuclear inclusions

 

The "Gold standard" for diagnosis of herpes virus is:

Virus isolation in cell culture

Infection of chick embryo

PCR

ELISA

Cytological research of smear

 

Herpes simplex virus type II infects:

Mucosae of the urogenital tract

Mucosa of the gastrointestinal tract

The eyes

Bronchial mucosa

Vascular endothelium

 

Herpes simplex virus type II are often transferred by:

Air - borne

Sexual transmission

The contact (through kissing, toys, household items)

The vertical path (of organs located below the upper)

Postnatally (after labor)

 

Herpes simplex virus type I most often affects:

Vascular endothelium

Mucosa of the gastrointestinal tract

Skin and eye mucosa, lips, nose,

Bronchial mucosa

Mucosae of the urogenital tract

 


 

The incubation period of herpes simplex virus is the average:

2-3 days

2-14 days

14-21 days

14-30 days

From 1 t3 months

 

Herpes simplex virus type II can be isolated from patient ‘s:

content of vesicles, vaginal secretions, semen

contents of vesicles, saliva

tears, saliva

bronchial washings, the contents of the vesicles. saliva

contents of vesicles

 

The prevalence of carriers of the herpes virus in Kazakhstan:

High

Very High

Low

Very low

Average

 

Is it necessary to examine a pregnant for the presence of herpes virus:

No, because the results do not affect the tactics of

Requires pregnant while taking on record

Requires up to 2 weeks before giving birth

Requires the third trimester of pregnancy

Required if a pregnant woman appeared clinical manifestations of infection

 

In which cases is there high risk neonatal herpes infection:

The primary infection of the mother before delivery (up to 2 weeks before delivery)

Recurrent infection during pregnancy

The carrier of the herpes virus

The primary infection of the future father of the baby, when the mother is pregnant

The primary infection of the mother at any stage of pregnancy

 

When does during herpes infection raise the question of operative delivery (because the risk of infection a child is 30-50 %) (order of Ministry of Health of the Republic of Kazakhstan № 239 of 07.04.10.):

The primary infection of the mother at any stage of the pregnancy

The primary infection of the mother in 2 weeks before labor

The primary infection of the mother in 3d trimester of the pregnancy

The primary infection of the mother in 3d trimester of the pregnancy

Recurrence of the disease in any stage of the pregnancy

 

What medicine is used to treat severe forms of herpes in the pregnancy:

Licorice (Glycyrrhiza glabra)

Garlic

Acyclovir

Olive Leaf Extract

Ehinoceya

 

One month old baby has the body temperature 40, the sharp pain in the mouth, salivation, mucous of gums and cheeks hyperemized, bubble elements. Your diagnosis is:

Thrush

Stomatitis

Herpes infection of the mucous

Enterovirus infection

Stevens-Jones’s syndrome

 

CMV infection

 

At postnatal CMV infection the incubation period is:

From 3 to 8 weeks

From 1 to 2 weeks

From 2 to 3 weeks

From 1 month. up to 3 months

From 3 months. up to 5 months

 

What is the percentage of the population infected with CMVI each year:

1-2%

5-6%

3-4%

8-9%

10-11%

 

 

Which week of the life of newborn babies of women suspected to CMV is the virus determined in urine, saliva or secretions from the throat:

1-2 nd week of life

3 weeks of life

1 weeks of life

2 weeks of life

4 weeks of life

 

What methods of CMV infection threaten to the life and health of the child:

Prenatal

Intrapartum (if the mother endocervicitis)

Failure of personal hygiene compliance of an infected mother (hand washing after using lavatory)

By saliva (by kissing of an infected adult)

Through breastfeeding

 

What group of viruses does cytomegalovirus (CMV) refer to:

Retroviruses

Herpes viruses

Rhabdovirus

Baculovirus

Paramyxovirus

 


 

The most informative material for the verification of CMVI in a patient is:

Urine

Blood

Saliva

Sputum, swabs from the throat

Scrapes and discharge from the genital tract

 

7 days-old child. Cytomegalovirus infection (CMVI) was diagnosed on the basis of clinical and laboratory data. Parents have been examined. A similar infection was revealed in the mother. Child is infected:

During the labor

Immediately after birth

During the gestation (in utero)

During the first breastfeeding

In the first days after birth

 

What congenital disease of the fetus is often caused by CMVI (Ailamazyan, 2007)

Disorder of a central nervous system

Vision Impairment

Hearing

Hip dysplasia

Gonadal dysgenesis in girls and boys

 

 

What is Cytotect, which is used for the treatment of cytomegalovirus infection in the newborn:

Antibiotic

Antiviral drug

Immunoglobulin

Non-steroidal anti-inflammatory drug

Antifungals

 

Indications for termination of pregnancy in the early period of cytomegalovirus infection:

Primary CMVI in pregnant

Connection of other viral infections

Media CMVI

The long history of the disease

Immunosuppressive condition of the pregnant

 

 

The source of the infection of cytomegalovirus infection can be:

Infected with HIV (human)

A sick man during acute phase of illness

The patient with lathen form of CMVI

A sick pet

Pet - a virus carrier

 

 


 

What is the course of CMVI during primary infection of humans with immunosuppression:

 

Asymptomatic
Acute Sialoadenit
Acute Bronchitis
Indolent Lymphadenitis
Generalized form of inflammation with severe disease

 

 

With what disease there is no need to carry out differential diagnostics of CMVI:

Listeria

Chickenpox

Toxoplasmosis

Herpes infection

Infectious mononucleosis

 

 

What complication of childbirth is most common in women with cytomegalovirus infection:

Metroendometritis

Mastitis

Sepsis

Diffuse purulent peritonitis

Parametritis

 

Please rate the result of ELISA for TORCH-infection (toxoplasmosisrubella cytomegalovirusherpes) Jg G-, JgM:

Acute infection

The early phase of acute infection

Acute exacerbation of chronic infection or

The state of immunity

The lack of immunity

 

Please rate the result of ELISA for TORSN infection (toxoplasmosisrubella cytomegalovirusherpes) Jg G, JgM -:

 

Generalised acute infection
The early phase of acute infection
Acute infection or exacerbation of chronic infection
State immunity
The lack of immunity

 

The signs, allowing to suspect a congenital CMV infection, are:

Abnormalities in the baby's condition at birth

Combinations of neurological symptoms with hepatosplenomegaly and protracted pneumonia

The wave protracted illness

The presence of atypical in peripheral blood mononuclear cells

The combination of all symptoms

 

 


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