Characterization of nucleic acids: DNA, RNA. Replication. Repair. Genetic code and its properties.
Questions to prepare for the topic:
1. What properties of DNA determine its role as a carrier of hereditary information.
2. The chemical organization of nucleic acids: the structure of nucleotides.
3. Define: nucleoside, nucleotide, mononucleotide, nucleic acid, nucleoprotein.
4. DNA structures (primary, secondary and tertiary) and their bonds.
5. The rules of E. Chargaff.
6. DNA model of J. Watson and F. Crick.
7. DNA properties.
8. DNA replication. DNA replication enzymes.
9. What is “locus ori”? Replication eye? Replication fork? How many replication initiation points do eukaryotes and prokaryotes have?
10. DNA repair.
11. What is a human genetic passport.
12. Features of the molecular organization of RNA.
13. Types and functions of RNA in the cell.
14. The genetic code and its properties.
1. To study and designate the structure of DNA.
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2. To study and designate the structure of tRNA.
Structure of tRNA: acceptor stem, pseudouracil loop, anticodon loop, dihydrouridine loop.
3. Indicate the differences between DNA and RNA.
| Stands For | DeoxyriboNucleicAcid. | RiboNucleicAcid. |
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| Base Pairing | ||
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4. In relation to the pictures below: a)explain three main steps in the process of DNA replication, b)name the enzymes that go with each step.
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