The mechanism of development.
Colonization resistance is violated and over-reproduce those species that are normally represented in a minimal amount, including opportunistic and putrefactive m / o, which produce toxic substances.
Disbiosis is characterized by:
1. A sharp decrease in the total number of m / o (some species completely disappear).
2. Predominance of the species that are normally represented in a minimum amount (or not at all): p. Pseudomonas, R.Proteus, R. Klebsiella, fungi of the R. Candida, staphylococci.
The following are some of the dysbiosis causes:
§ Antibiotic use: Antibiotics seem to be prescribed for everything these days, especially when they are not needed (i.e. in cases of the common cold, the flu, bronchitis, most sore throats, and many ear and sinus infections). Every time antibiotics are taken, they kill all the bacteria—even the “good” kind. Over prescribing antibiotics will also cause antibiotic resistance, which means the antibiotics don’t only kill the “good bacteria,” but they may not even help in cases of bacterial infections.
§ Use of other drugs: Proton-pump inhibitors and antacids are designed to block hydrochloric acid production in the stomach, but that acid is the first line of defense against microbes that enter the body with food. When that acid is blocked, the body no longer defends against the “bad microbes.” The overuse of non-steroidal anti-inflammatory drugs (NSAIDs) also inhibits the growth of the “good bacteria.”
§ Fermentation: Small intestinal bacterial overgrowth (SIBO) is a carbohydrate intolerance condition induced by bacterial overgrowth in the small intestine, large intestine, and stomach. Any carbohydrate will ferment by the “bad bacteria” and produce toxic waste products as a result.
§ Chronic stress: Chronic stress will increase hormone levels, and this also highly impairs the immune system, which creates an environment in the GI tract that is susceptible to dysbiosis.
§ Poor diet: A poor diet is another major factor in dysbiosis. Low-fiber diets, high-fat and high-protein diets, and diets high in sugar and processed foods can slow down gut motility, and also often lack nutrients necessary to nourish and repair the digestive organs, including the GI tract. Candida is a type of yeast that lives off sugar and processed foods, which highly disturb the balance of organisms in the body. Gluten sensitivity is also a factor in dysbiosis.
§ Environmental factors: Environmental factors that influence dysbiosis include contaminated food and water, exposure to manufactured chemicals or toxic metals, the presence of fungus or mold in the home, and living in a foggy or damp climate.
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Signs and Symptoms of Dysbiosis
§ The common digestive issues will include chronic diarrhea, heartburn, chronic constipation, bloating, belching, abdominal pain, frequent indigestion, bad breath, foul-smelling stools, undigested food in the stool.
Gut dysbiosis can lead to intestinal lining changes, which then increases the permeability of the intestine. This results in leaky gut syndrome—also called increased intestinal permeability. Basically, the lining of the intestines and bowel loses its integrity, which opens the door to parasites, viruses, bacteria, and also undigested food molecules. The aggravated immune system will also become unstable, and may attack the body and even lead to autoimmune diseases.
Natural Treatment for Dysbiosis.
In general, dysbiosis symptoms and treatment go hand in hand. This means that the dysbiosis treatment should be based on a person’s symptoms and conditions. The first step in the treatment of dysbiosis is the removal of various aggravating factors like antibiotics, other drugs, and certain dietary factors that may be the cause of the bacterial or organism overgrowth. Some drugs used in a dysbiosis treatment may include rifaxamin, ciprofloxacin, norfloxacin, or co-trimoxazole. However, there are also several remedies used in a natural dysbiosis treatment that may be useful as well.
For restoration of normal flora, sometimes bacterial preparations are used probiotics: eubiotics, prebiotics and synbiotics. Eubiotics are prepared from live strains or bacterial metabolites. Examples of monocomponent preparations are ‘Bifidumbacterin’, ‘Lactobacterin’, ‘Colibacterin’, and polycomponent ones: ‘Bffilong’ (contains B. bifidum and B. longum), ‘Linex’ (B. acidophilus, B. infantis, E. faecalis).
During the recent years, apart from liophilized (dried) formulations, liquid preparations from Bifidobacterium spp. and Lactobacillus spp. are started to be used, followed by production of soured milk products. It is considered to be that efficacy of such preparation might be higher, because they already contain ready-to-use biologically active compounds and also activity of bacteria themselves is higher.
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Prebioticsare thought to stimulate the activity and growth of of the “good bacteria.” in the gut. That is why it is a good idea to also take supplements with prebiotics like fructooligosaccharides (FOS), inulin, citrus pectin, and high-soluble fiber from psyllium. Lactulose is a disaccharide, which also applies to prebiotics.
Synbiotic- contain live microorganisms and prebiotics.
Complications of Dysbiosis
There are various complications of gut dysbiosis. Here is a deeper look at some of the complications and conditions that may result from dysbiosis:
§ Atopic eczema: Skin conditions are a common result of dysbiosis, but especially atopic eczema. Most atopic eczema patients have malabsorption and intestinal dysbiosis.
§ Candida: Candida is the condition where fungus and yeast will grow out of control, and lead to certain debilitating symptoms like persistent fatigue, muscle pain, constipation, and rectal itching.
§ Irritable bowel syndrome: Various studies have found that IBS patients have a greater likelihood of abnormal fecal flora.
§ Other possible dysbiosis complications: When dysbiosis is left untreated it can lead to severe fungal infections, and even increase the risk of cancer.
Prevention of Dysbiosis
It is always better to prevent a disease or condition from starting in the first place. The following are a few gut dysbiosis prevention methods:
§ Eat an overall healthy and clean diet that contains lots of green leafy vegetables, organic meats, and totally avoid processed foods.
§ Avoid alcohol or extremely limit your intake to once every few months. All forms of alcohol contain acetaldehyde, yeast, and other ingredients that harm the balance of bacteria and other organisms in the GI tract.
§ Avoid antibiotics, and other drugs like proton-pump inhibitors, antacids, non-steroidal anti-inflammatory drugs (NSAIDs). All of these drugs inhibit the growth of “good” bacteria in the GI tract and rest of the body.
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